STK4 anticorps (AA 324-452)

N° du produit ABIN7601330

Cet anticorps anti-STK4 est un anticorps Lapin Polyclonal détectant STK4 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour STK4 anticorps (AA 324-452) (ABIN7601330)

Antigène: STK4 (serine/threonine Kinase 4 (STK4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STK4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-STK4 anticorps

Épitope: AA 324-452

Fonction: Anti-MST1/STK4 Antibody Picoband®

Attributs du produit: Anti-MST1/STK4 Antibody Picoband® (ABIN7601330). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MST1/STK4 recombinant protein (Position: E324-D452). Human STK4 shares 93.8% amino acid (aa) sequence identity with mouse STK4.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Abdollahpour, H., Appaswamy, G., Kotlarz, D., Diestelhorst, J., Beier, R., Schaffer, A. A., Gertz, E. M., Schambach, A., Kreipe, H. H., Pfeifer, D., Engelhardt, K. R., Rezaei, N., Grimbacher, B., Lohrmann, S., Sherkat, R., Klein, C. The phenotype of human STK4 deficiency. Blood 119: 3450-3457, 2012. 2. Cheung, W. L., Ajiro, K., Samejima, K., Kloc, M., Cheung, P., Mizzen, C. A., Beeser, A., Etkin, L. D., Chernoff, J., Earnshaw, W. C., Allis, C. D. Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell 113: 507-517, 2003. 3. Creasy, C. L., Chernoff, J. Cloning and characterization of a human protein kinase with homology to Ste20. J. Biol. Chem. 270: 21695-21700, 1995.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur STK4

Antigène: STK4 (serine/threonine Kinase 4 (STK4))

Autre désignation: MST1/STK4

Sujet: Serine/threonine-protein kinase 4 is an enzyme that in humans is encoded by the STK4 gene. The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Poids moléculaire: 56 kDa

ID gène: 6789

UniProt: Q13043

Pathways: Tube Formation