Recoverin anticorps (AA 33-150)

N° du produit ABIN7601337

Cet anticorps Lapin Polyclonal détecte spécifiquement Recoverin dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour Recoverin anticorps (AA 33-150) (ABIN7601337)

Antigène: Recoverin (RCVRN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Recoverin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Recoverin anticorps

Épitope: AA 33-150

Fonction: Anti-Recoverin/RCVRN Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Recoverin/RCVRN Antibody Picoband® (ABIN7601337). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Recoverin/RCVRN recombinant protein (Position: Q33-K150).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bayes, M., Valverde, D., Balcells, S., Grinberg, D., Vilageliu, L., Benitez, J., Ayuso, C., Beneyto, M., Baiget, M., Gonzalez-Duarte, R. Evidence against involvement of recoverin in autosomal recessive retinitis pigmentosa in 42 Spanish families. Hum. Genet. 96: 89-94, 1995. 2. Dizhoor, A. M., Ray, S., Kumar, S., Niemi, G., Spencer, M., Brolley, D., Walsh, K. A., Philipov, P. P., Hurley, J. B., Stryer, L. Recoverin: a calcium sensitive activator of retinal rod guanylate cyclase. Science 251: 915-918, 1991. 3. Freund, C. L., Valle, D. Cloning and initial characterization of the cDNA and gene for human recoverin. (Abstract) Am. J. Hum. Genet. 51 (suppl.): A6 only, 1992.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur Recoverin

Antigène: Recoverin (RCVRN)

Autre désignation: RCVRN

Sujet:

Synonyms: Disintegrin and metalloproteinase domain-containing protein 28,ADAM 28,3.4.24.-,Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II,eMDC II,Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L,MDC-L,ADAM28,ADAM23, MDCL,

Tissue Specificity: Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen.

Background: This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.

Poids moléculaire: 26 kDa

ID gène: 5957

UniProt: P35243

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction