SRP72 anticorps (AA 40-460)
Aperçu rapide pour SRP72 anticorps (AA 40-460) (ABIN7601648)
Antigène
Voir toutes SRP72 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 40-460
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Fonction
- Anti-SRP72 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-SRP72 Antibody (ABIN7601648). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human SRP72 recombinant protein (Position: I40-Y460).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SRP72 (Signal Recognition Particle 72kDa (SRP72))
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Autre désignation
- SRP72
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Sujet
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Synonyms: Golgin subfamily A member 2, 130 kDa cis-Golgi matrix protein
Tissue Specificity: Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.
Background: This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
- 75 kDa
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ID gène
- 6731
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UniProt
- O76094
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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