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MCF2 anticorps (AA 42-925)

Cet anticorps anti-MCF2 est un anticorps Lapin Polyclonal détectant MCF2 dans WB, ELISA et FACS. Adapté pour Humain.
N° du produit ABIN7601702

Aperçu rapide pour MCF2 anticorps (AA 42-925) (ABIN7601702)

Antigène

Voir toutes MCF2 Anticorps
MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Reactivité

  • 19
  • 2
Humain

Hôte

  • 18
  • 1
Lapin

Clonalité

  • 19
Polyclonal

Conjugué

  • 10
  • 3
  • 2
  • 2
  • 1
  • 1
Cet anticorp MCF2 est non-conjugé

Application

  • 15
  • 12
  • 11
  • 10
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Épitope

    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 42-925

    Fonction

    Anti-DBL Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins

    Attributs du produit

    Anti-DBL Antibody Picoband® (ABIN7601702). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human DBL recombinant protein (Position: D42-Y925).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Anson, D. S., Blake, D. J., Winship, P. R., Birnbaum, D., Brownlee, G. G. Nullisomic deletion of the mcf.2 transforming gene in two haemophilia B patients. EMBO J. 7: 2795-2799, 1988. 2. Eva, A., Aaronson, S. A. Isolation of a new human oncogene from a diffuse B-cell lymphoma. Nature 316: 273-275, 1985. 3. Eva, A., Vecchio, G., Rao, C. D., Tronick, S. R., Aaronson, S. A. The predicted DBL oncogene product defines a distinct class of transforming proteins. Proc. Nat. Acad. Sci. 85: 2061-2065, 1988.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

    Autre désignation

    MCF2

    Sujet

    Synonyms: Protein phosphatase 1 regulatory subunit 14A,17 kDa PKC-potentiated inhibitory protein of PP1,Protein kinase C-potentiated inhibitor protein of 17 kDa,CPI-17,PPP1R14A,CPI17, PPP1INL,

    Tissue Specificity: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. .

    Background: The DBL proto-oncogene is a protein that in humans is encoded by the MCF2 gene. The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.

    Poids moléculaire

    125 kDa

    ID gène

    4168

    UniProt

    P10911
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