SHROOM2 anticorps (AA 427-1138)

N° du produit ABIN7601707

L’anticorps Lapin Polyclonal anti-SHROOM2 a été validé pour ELISA, WB et FACS. Il convient pour détecter SHROOM2 dans des échantillons de Humain.

Aperçu rapide pour SHROOM2 anticorps (AA 427-1138) (ABIN7601707)

Antigène: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHROOM2 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-SHROOM2 anticorps

Épitope: AA 427-1138

Fonction: Anti-SHROOM2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SHROOM2 Antibody Picoband® (ABIN7601707). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SHROOM2 recombinant protein (Position: R427-H1138).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dietz, M. L., Bernaciak, T. M., Vendetti, F., Kielec, J. M., Hildebrand, J. D. Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins. J. Biol. Chem. 281: 20542-20554, 2006. 2. Dinulos, M. B., Bassi, M. T., Rugarli, E. I., Chapman, V., Ballabio, A., Disteche, C. M. A new region of conservation is defined between human and mouse X chromosomes. Genomics 35: 244-247, 1996. 3. Schiaffino, M. V., Bassi, M. T., Rugarli, E. I., Renieri, A., Galli, L., Ballabio, A. Cloning of a human homologue of the Xenopus laevis APX gene from the ocular albinism type 1 critical region. Hum. Molec. Genet. 4: 373-382, 1995.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SHROOM2

Antigène: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Autre désignation: SHROOM2

Sujet:

Synonyms: Epigen,Epithelial mitogen,EPG,Epgn,

Background: Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene. This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 180 kDa

ID gène: 357

UniProt: Q13796

Pathways: Cell-Cell Junction Organization, Asymmetric Protein Localization