Cadherin 5 anticorps (AA 48-272) (DyLight 488)

N° du produit ABIN7601830

L’anticorps Souris Monoclonal anti-Cadherin 5 a été validé pour FACS. Il convient pour détecter Cadherin 5 dans des échantillons de Humain.

Aperçu rapide pour Cadherin 5 anticorps (AA 48-272) (DyLight 488) (ABIN7601830)

Antigène: Cadherin 5 (CDH5)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin 5 est conjugé à/à la DyLight 488

Application: Flow Cytometry (FACS)

Clone: 3D4

Détail du produit anti-Cadherin 5 anticorps (DyLight 488)

Épitope: AA 48-272

Fonction: Anti-Human VE-Cadherin CDH5 DyLight® 488 conjugated Antibody(monoclonal, 3D4)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Human VE-Cadherin CDH5 DyLight® 488 conjugated Antibody (monoclonal, 3D4) (ABIN7606684)-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Immunogène: E. coli-derived human VE Cadherin recombinant protein (Position: D48-R272).

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, human
1. Huber, P., Dalmon, J., Engiles, J., Breviario, F., Gory, S., Siracusa, L. D., Buchberg, A. M., Dejana, E. Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (Cdh5). Genomics 32: 21-28, 1996. 2. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Détails sur Cadherin 5

Antigène: Cadherin 5 (CDH5)

Autre désignation: CDH5

Sujet:

Synonyms: Cadherin-5, 7B4 antigen, Vascular endothelial cadherin, VE-cadherin, CD144, CDH5

Background: CDH5 (Cadherin 5), also known as VE-cadherin, is a type of cadherin. It is encoded by the human gene CDH5. This gene is mapped to 16q22.1 using somatic cell hybrid panels. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Therefore it was concluded that VE-cadherin serves the purpose of maintaining newly formed vessels.

Poids moléculaire: 39 kDa

ID gène: 1003

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2