Peroxiredoxin 2 anticorps (AA 5-127)

N° du produit ABIN7601867

Cet anticorps anti-Peroxiredoxin 2 est un anticorps Lapin Polyclonal détectant Peroxiredoxin 2 dans WB, ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour Peroxiredoxin 2 anticorps (AA 5-127) (ABIN7601867)

Antigène: Peroxiredoxin 2 (PRDX2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Peroxiredoxin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Peroxiredoxin 2 anticorps

Épitope: AA 5-127

Fonction: Anti-peroxiredoxin 2/PRDX2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-peroxiredoxin 2/PRDX2 Antibody Picoband® (ABIN7601867). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human peroxiredoxin 2/PRDX2 recombinant protein (Position: N5-R127).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Choi, M. H., Lee, I. K., Kim, G. W., Kim, B. U., Han, Y.-H., Yu, D.-Y., Park, H. S., Kim, K. Y., Lee, J. S., Choi, C., Bae, Y. S., Lee, B. I., Rhee, S. G., Kang, S. W. Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II. Nature 435: 347-353, 2005. 2. Lee, T.-H., Kim, S.-U., Yu, S.-L., Kim, S. H., Park, D. S., Moon, H.-B., Dho, S. H., Kwon, K.-S., Kwon, H. J., Han, Y.-H., Jeong, S., Kang, S. W., Shin, H.-S., Lee, K.-K., Rhee, S. G., Yu, D.-Y. Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice. Blood 101: 5033-5038, 2003. 3. Pahl, P., Berger, R., Hart, I., Chae, H. Z., Rhee, S. G., Patterson, D. Localization of TDPX1, a human homologue of the yeast thioredoxin-dependent peroxide reductase gene (TPX), to chromosome 13q12. Genomics 26: 602-606, 1995.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur Peroxiredoxin 2

Antigène: Peroxiredoxin 2 (PRDX2)

Autre désignation: PRDX2

Sujet:

Synonyms: Neuronal acetylcholine receptor subunit alpha-3, CHRNA3, NACHRA3

Background: PRDX2(peroxiredoxin 2) also known as NKEFB, PRP, PRX2, PRXII or TPX1, is a?protein?that in humans is encoded by the?PRDX2?gene. This gene encodes a member of the peroxiredoxin family of antioxidant?enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides.?The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The?Prdx2?-/- mice were healthy in appearance and fertile. Choi et al.(2005)?demonstrated that?PRDX2?is a negative regulator of PDGF signaling. Prx II deficiency results in increased production of peroxide, enhanced activation of PDGF receptor and phospholipase C-gamma-1, and subsequently increased cell proliferation and migration in response to PDGF. PRX2 accounted for about half of the thioredoxin activity in parasite extracts, and PRX2 expression was increased in the presence of chloroquine, regardless of P. falciparum strain susceptibility to the drug.

Poids moléculaire: 22 kDa

ID gène: 7001

UniProt: P32119