Neuropilin 1 anticorps (AA 504-827)
Aperçu rapide pour Neuropilin 1 anticorps (AA 504-827) (ABIN7601921)
Antigène
Voir toutes Neuropilin 1 (NRP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 504-827
-
Fonction
- Anti-Neuropilin 1 Antibody (monoclonal, 8G6G7)
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins.
-
Homologie
- Human Neuropilin 1 shares 95%,94% amino acid (aa) sequences identity with mouse,rat Neuropilin 1,respectively.
-
Attributs du produit
- Anti-Neuropilin 1 Antibody.(monoclonal, 8G6G7)-2. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- E.coli-derived human Neuropilin 1 recombinant protein (Position: K504-T827). Human Neuropilin 1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Neuropilin 1, respectively.
-
Isotype
- IgG2a
-
-
-
-
Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
-
-
- Neuropilin 1 (NRP1)
-
Autre désignation
- NRP1
-
Sujet
-
Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Gene Full Name: neuropilin 1
-
Poids moléculaire
- 120 kDa
-
ID gène
- 8829
-
UniProt
- O14786
-
Pathways
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
Antigène
-