EDEM3 anticorps (AA 54-795)

N° du produit ABIN7602003

Cet anticorps Lapin Polyclonal détecte spécifiquement EDEM3 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour EDEM3 anticorps (AA 54-795) (ABIN7602003)

Antigène: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDEM3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-EDEM3 anticorps

Épitope: AA 54-795

Fonction: Anti-EDEM3 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-EDEM3 Antibody Picoband® (ABIN7602003). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human EDEM3 recombinant protein (Position: N54-D795).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hirao, K., Natsuka, Y., Tamura, T., Wada, I., Morito, D., Natsuka, S., Romero, P., Sleno, B., Tremblay, L. O., Herscovics, A., Nagata, K., Hosokawa, N. EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming. J. Biol. Chem. 281: 9650-9658, 2006. 2. Sood, R., Bonner, T. I., Makalowska, I., Stephan, D. A., Robbins, C. M., Connors, T. D., Morgenbesser, S. D., Su, K., Faruque, M. U., Pinkett, H., Graham, C., Baxevanis, A. D., Klinger, K. W., Landes, G. M., Trent, J. M., Carpten, J. D. Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. Genomics 73: 211-222, 2001.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur EDEM3

Antigène: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Autre désignation: EDEM3

Sujet:

Synonyms: Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA

Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Background: ER degradation-enhancing alpha-mannosidase-like 3 is an enzyme that in humans is encoded by the EDEM3 gene. Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER.

Poids moléculaire: 105 kDa

ID gène: 80267

Pathways: SARS-CoV-2 Protein Interactome