ZNRF3 anticorps (AA 54-913)

N° du produit ABIN7602004

L’anticorps Lapin Polyclonal anti-ZNRF3 a été validé pour ELISA, WB, IF, FACS et ICC. Il convient pour détecter ZNRF3 dans des échantillons de Humain.

Aperçu rapide pour ZNRF3 anticorps (AA 54-913) (ABIN7602004)

Antigène: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNRF3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-ZNRF3 anticorps

Épitope: AA 54-913

Fonction: Anti-ZNRF3 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-ZNRF3 Antibody Picoband® (ABIN7602004). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ZNRF3 recombinant protein (Position: R54-E913).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hao, H.-X., Xie, Y., Zhang, Y., Charlat, O., Oster, E., Avello, M., Lei, H., Mickanin, C., Liu, D., Ruffner, H., Mao, X., Ma, Q., Zamponi, R., Bouwmeester, T., Finan, P. M., Kirschner, M. W., Porter, J. A., Serluca, F. C., Cong, F. ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. Nature 485: 195-200, 2012. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 5/16/2008. 3. Hirosawa, M., Nagase, T., Ishikawa, K., Kikuno, R., Nomura, N., Ohara, O. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. DNA Res. 6: 329-336, 1999.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur ZNRF3

Antigène: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Autre désignation: ZNRF3

Sujet:

Synonyms: Cerebellar degeneration-related protein 2, Major Yo paraneoplastic antigen, Paraneoplastic cerebellar degeneration-associated antigen, CDR2, PCD17

Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.

Background: Enables frizzled binding activity and ubiquitin-protein transferase activity. Involved in cellular protein metabolic process and negative regulation of Wnt signaling pathway. Is integral component of plasma membrane.

Poids moléculaire: 130 kDa

ID gène: 84133

Pathways: Signalisation WNT