SRPRB anticorps (AA 55-271)

N° du produit ABIN7602015

Cet anticorps Lapin Polyclonal détecte spécifiquement SRPRB dans WB, ELISA, IHC, IF, ICC et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour SRPRB anticorps (AA 55-271) (ABIN7602015)

Antigène: SRPRB (Signal Recognition Particle Receptor, B Subunit (SRPRB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRPRB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-SRPRB anticorps

Épitope: AA 55-271

Fonction: Anti-SRPRB Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-SRPRB Antibody Picoband® (ABIN7602015). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SRPRB recombinant protein (Position: K55-A271).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 3/28/2016. 2. Legate, K. R., Falcone, D., Andrews, D. W. Nucleotide-dependent binding of the GTPase domain of the signal recognition particle receptor beta-subunit to the alpha-subunit. J. Biol. Chem. 275: 27439-27446, 2000. 3. Miller, J. D., Tajima, S., Lauffer, L., Walter, P. The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane. J. Cell Biol. 128: 273-282, 1995.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SRPRB

Antigène: SRPRB (Signal Recognition Particle Receptor, B Subunit (SRPRB))

Autre désignation: SRPRB

Sujet:

Synonyms: RNA-binding protein 47,RNA-binding motif protein 47,RBM47,

Tissue Specificity: Abundantly expressed in tonsil, lymph node, and trachea, strong expression in prostate, lower expression in thyroid, stomach, and colon. .

Background: Signal recognition particle receptor subunit beta is a protein that in humans is encoded by the SRPRB gene. The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.

Poids moléculaire: 30 kDa

ID gène: 58477

UniProt: Q9Y5M8

Pathways: ER-Nucleus Signaling