DRD4 anticorps (AA 57-387)

N° du produit ABIN7602065

Cet anticorps anti-DRD4 est un anticorps Lapin Polyclonal détectant DRD4 dans WB, ELISA et FACS. Adapté pour Souris et Rat.

Aperçu rapide pour DRD4 anticorps (AA 57-387) (ABIN7602065)

Antigène: DRD4 (Dopamine Receptor D4 (DRD4))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRD4 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-DRD4 anticorps

Épitope: AA 57-387

Fonction: Anti-DRD4 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-DRD4 Antibody Picoband® (ABIN7602065). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse DRD4 recombinant protein (Position: A57-C387).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse
ELISA, 0.1-0.5 μg/mL,
1. D'Souza, U. M., Russ, C., Tahir, E., Mill, J., McGuffin, P., Asherson, P. J., Craig, I. W. Functional effects of a tandem duplication polymorphism in the 5-prime flanking region of the DRD4 gene. Biol. Psychiat. 56: 691-697, 2004. 2. De Luca, A., Rizzardi, M., Buccino, A., Alessandroni, R., Salvioli, G. P., Filograsso, N., Novelli, G., Dallapiccola, B. Association of dopamine D4 receptor (DRD4) exon III repeat polymorphism with temperament in 3-year-old infants. Neurogenetics 4: 207-212, 2003. 3. De Luca, A., Rizzardi, M., Torrente, I., Alessandroni, R., Salvioli, G. P., Filograsso, N., Dallapiccola, B., Novelli, G. Dopamine D4 receptor (DRD4) polymorphism and adaptability trait during infancy: a longitudinal study in 1- to 5-month-old neonates. Neurogenetics 3: 79-82, 2001.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur DRD4

Antigène: DRD4 (Dopamine Receptor D4 (DRD4))

Autre désignation: Drd4

Sujet:

Synonyms: D (4) dopamine receptor; D (2C) dopamine receptor; Dopamine D4 receptor; Drd4

Tissue Specificity: Found only in peripheral nervous system Schwann cells.

Background: D (4) dopamine receptor is a protein that in humans is encoded by the Drd4 gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 48 kDa

ID gène: 13491

UniProt: P51436

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity