TULP3 anticorps (AA 62-362)

N° du produit ABIN7602191

Cet anticorps anti-TULP3 est un anticorps Lapin Polyclonal détectant TULP3 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour TULP3 anticorps (AA 62-362) (ABIN7602191)

Antigène: TULP3 (Tubby Like Protein 3 (TULP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TULP3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TULP3 anticorps

Épitope: AA 62-362

Fonction: Anti-TULP3 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TULP3 Antibody Picoband® (ABIN7602191). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TULP3 recombinant protein (Position: P62-H362).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Devane, J., Ott, E., Olinger, E. G., Epting, D., Decker, E., Friedrich, A., Bachmann, N., Renschler, G., Eisenberger, T., Briem-Richter, A., Grabhorn, E. F., Powell, L., and 24 others. Progressive liver, kidney, and heart degeneration in children and adults affected by TULP3 mutations. Am. J. Hum. Genet. 109: 928-943, 2022. 2. Ikeda, A., Ikeda, S., Gridley, T., Nishina, P. M., Naggert, J. K. Neural tube defects and neuroepithelial cell death in Tulp3 knockout mice. Hum. Molec. Genet. 10: 1325-1334, 2001. 3. Nishina, P. M., North, M. A., Ikeda, A., Yan, Y., Naggert, J. K. Molecular characterization of a novel tubby gene family member, TULP3, in mouse and humans. Genomics 54: 215-220, 1998.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TULP3

Antigène: TULP3 (Tubby Like Protein 3 (TULP3))

Autre désignation: TULP3

Sujet:

Synonyms: B-cell differentiation antigen CD72, Lyb-2, CD72, CD72

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Poids moléculaire: 60 kDa

ID gène: 7289

UniProt: O75386

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation