Spectrin beta Chain, Erythrocyte (SPTB) (AA 703-2137) anticorps
Aperçu rapide pour Spectrin beta Chain, Erythrocyte (SPTB) (AA 703-2137) anticorps (ABIN7602356)
Antigène
Voir toutes Spectrin beta Chain, Erythrocyte (SPTB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 703-2137
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Fonction
- Anti-beta 1 Spectrin/SPTB Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-beta 1 Spectrin/SPTB Antibody (ABIN7602356). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human beta 1 Spectrin/SPTB recombinant protein (Position: M703-Y2137).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Spectrin beta Chain, Erythrocyte (SPTB)
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Autre désignation
- SPTB
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Sujet
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Synonyms: Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1, Caspase-2 subunit p18, Caspase-2 subunit p13, Caspase-2 subunit p12, CASP2, ICH1, NEDD2
Tissue Specificity: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Background: Spectrin beta chain, erythrocyte is a protein that in humans is encoded by the SPTB gene. This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described.
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Poids moléculaire
- 270 kDa
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ID gène
- 6710
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UniProt
- P11277
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Pathways
- Regulation of Actin Filament Polymerization
Antigène
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