GGCX anticorps (AA 75-730)
Aperçu rapide pour GGCX anticorps (AA 75-730) (ABIN7602419)
Antigène
Voir toutes GGCX AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 75-730
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Fonction
- Anti-GGCX Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-GGCX Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human GGCX recombinant protein (Position: M75-A730).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.25 μg/mL, Human, Mouse Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- GGCX (gamma-Glutamyl Carboxylase (GGCX))
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Autre désignation
- GGCX
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Sujet
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Background: Gamma-glutamyl carboxylase is an enzyme that in humans is encoded by the GGCX gene, located on chromosome 2 at 2p12. This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants.
Gene Full Name: gamma-glutamyl carboxylase
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Poids moléculaire
- 88 kDa
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ID gène
- 2677
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UniProt
- P38435
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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