PIK3AP1 anticorps (AA 78-583)

N° du produit ABIN7602451

L’anticorps anti-PIK3AP1 Polyclonal Lapin est utilisé pour la détection de PIK3AP1 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour PIK3AP1 anticorps (AA 78-583) (ABIN7602451)

Antigène: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3AP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PIK3AP1 anticorps

Épitope: AA 78-583

Fonction: Anti-PIK3AP1 Antibody

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PIK3AP1 shares 83.8% amino acid (aa) sequence identity with mouse PIK3AP1.

Attributs du produit: Anti-PIK3AP1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PIK3AP1 recombinant protein (Position: H78-R583). Human PIK3AP1 shares 83.8% amino acid (aa) sequence identity with mouse PIK3AP1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PIK3AP1

Antigène: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Autre désignation: PIK3AP1

Sujet:

Background: Phosphoinositide 3-kinase adapter protein 1 is an enzyme that in humans is encoded by the PIK3AP1 gene. BCAP (B cell adaptor for phosphoinositide 3-kinase (PI3K)), also known as PI3KAP1, participates in linking the B cell antigen receptor (BCR) with the PI3K pathway. Tyrosine phosphorylation of BCAP by BCR-associated protein tyrosine kinases, such as Syk and Btk, generates binding sites for the p85 subunit of PI3K, resulting in activation of the PI3K pathway. Human and mouse BCAP contain 3 YXXM SH2 binding motifs for interaction with PI3K. BCAP null mice have deficient immune function, with B cells that exhibit enhanced apoptosis.

Gene Full Name: phosphoinositide-3-kinase adaptor protein 1

Poids moléculaire: 90 kDa

ID gène: 118788

UniProt: Q6ZUJ8

Pathways: Activation of Innate immune Response, BCR Signaling, L'effet Warburg