NNMT anticorps (AA 8-264)

N° du produit ABIN7602474

Cet anticorps Lapin Polyclonal détecte spécifiquement NNMT dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour NNMT anticorps (AA 8-264) (ABIN7602474)

Antigène: NNMT (Nicotinamide N-Methyltransferase (NNMT))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NNMT est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NNMT anticorps

Épitope: AA 8-264

Fonction: Anti-NNMT Antibody Picoband®

Attributs du produit: Anti-NNMT Antibody Picoband® (ABIN7602474). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NNMT recombinant protein (Position: K8-L264). Human NNMT shares 85.1% amino acid (aa) sequence identity with mouse NNMT.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Aksoy, S., Brandriff, B. F., Ward, A., Little, P. F. R., Weinshilboum, R. M. Human nicotinamide N-methyltransferase gene: molecular cloning, structural characterization and chromosomal localization. Genomics 29: 555-561, 1995. 2. Aksoy, S., Szumlanski, C. L., Weinshilboum, R. M. Human liver nicotinamide N-methyltransferase: cDNA cloning, expression, and biochemical characterization. J. Biol. Chem. 269: 14835-14840, 1994. 3. Eckert, M. A., Coscia, F., Chryplewicz, A., Chang, J. W., Hernandez, K. M., Pan, S., Tienda, S. M., Nahotko, D. A., Li, G., Blazenovic, I., Lastra, R. R., Curtis, M., Yamada, S. D., Perets, R., McGregor, S. M., Andrade, J., Fiehn, O., Moellering, R. E., Mann, M., Lengyel, E. Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature 569: 723-728, 2019.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur NNMT

Antigène: NNMT (Nicotinamide N-Methyltransferase (NNMT))

Autre désignation: NNMT

Sujet: Nicotinamide N-methyltransferase (NNMT) is an enzyme that in humans is encoded by the NNMT gene. N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.

Poids moléculaire: 28 kDa

ID gène: 4837

UniProt: P40261