TTI2 anticorps (AA 80-508)

N° du produit ABIN7602516

Cet anticorps Lapin Polyclonal détecte spécifiquement TTI2 dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour TTI2 anticorps (AA 80-508) (ABIN7602516)

Antigène: TTI2 (TELO2 Interacting Protein 2 (TTI2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTI2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-TTI2 anticorps

Épitope: AA 80-508

Fonction: Anti-TTI2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TTI2 Antibody Picoband® (ABIN7602516). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TTI2 recombinant protein (Position: E80-T508).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 1/11/2012. 2. Hurov, K. E., Cotta-Ramusino, C., Elledge, S. J. A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability. Genes Dev. 24: 1939-1950, 2010. 3. Langouet, M., Saadi, A., Rieunier, G., Moutton, S., Siquier-Pernet, K., Fernet, M., Nitschke, P., Munnich, A., Stern, M.-H., Chaouch, M., Colleaux, L. Mutation in TTI2 reveals a role for triple T complex in human brain development. Hum. Mutat. 34: 1472-1476, 2013.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TTI2

Antigène: TTI2 (TELO2 Interacting Protein 2 (TTI2))

Autre désignation: TTI2

Sujet:

Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8, CPAMD8, KIAA1283

Tissue Specificity: Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine. Expressed in the lens, cornea and retina. Strongly expressed in the distal tips of the retinal neuroepithelium that form the iris and ciliary body.

Background: TELO2 interacting protein 2 is a protein that in humans is encoded by the TTI2 gene. This gene encodes a regulator of the DNA damage response. The protein is a component of the Triple T complex (TTT) which also includes telomere length regulation protein and TELO2 interacting protein 1. The TTT complex is involved in cellular resistance to DNA damage stresses and may act as a regulator of phosphoinositide-3-kinase-related protein kinase (PIKK) abundance.

Poids moléculaire: 60 kDa

ID gène: 80185