WDR33 anticorps (AA 88-525)
Aperçu rapide pour WDR33 anticorps (AA 88-525) (ABIN7602597)
Antigène
Voir toutes WDR33 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 88-525
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Fonction
- Anti-WDR33 Antibody Picoband®
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-WDR33 Antibody Picoband® (ABIN7602597). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human WDR33 recombinant protein (Position: Y88-R525).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chan, S. L., Huppertz, I., Yao, C., Weng, L., Moresco, J. J., Yates, J. R., III, Ule, J., Manley, J. L., Shi, Y. CPSF30 and Wdr33 ly bind to AAUUAAA in mammalian mRNA 3-prime processing. Genes Dev. 28: 2370-2380, 2014. 2. Gross, M. B. Personal Communication. Baltimore, Md. 8/9/2018. 3. Ito, S., Sakai, A., Nomura, T., Miki, Y., Ouchida, M., Sasaki, J., Shimizu, K. A novel WD40 repeat protein, WDC146, highly expressed during spermatogenesis in a stage-specific manner. Biochem. Biophys. Res. Commun. 280: 656-663, 2001. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- WDR33 (WD Repeat Domain 33 (WDR33))
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Autre désignation
- WDR33
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Sujet
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Synonyms: Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20, TRF-proximal protein homolog, hTRFP, MED20, TRFP,
Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.
Background: WD repeat-containing protein 33 is a protein that in humans is encoded by the WDR33 gene. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Poids moléculaire
- 170-180 kDa
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ID gène
- 55339
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UniProt
- Q9C0J8
Antigène
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