TOM1L1 anticorps (AA 9-448)

N° du produit ABIN7602631

L’anticorps Lapin Polyclonal anti-TOM1L1 a été validé pour WB, ELISA, IHC, IF et FACS. Il convient pour détecter TOM1L1 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour TOM1L1 anticorps (AA 9-448) (ABIN7602631)

Antigène: TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOM1L1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-TOM1L1 anticorps

Épitope: AA 9-448

Fonction: Anti-TOM1L1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TOM1L1 Antibody Picoband® (ABIN7602631). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TOM1L1 recombinant protein (Position: D9-D448).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Franco, M., Furstoss, O., Simon, V., Benistant, C., Hong, W. J., Roche, S. The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors. Molec. Cell. Biol. 26: 1932-1947, 2006. 2. Gross, M. B. Personal Communication. Baltimore, Md. 7/12/2012. 3. Katoh, Y., Imakagura, H., Futatsumori, M., Nakayama, K. Recruitment of clathrin onto endosomes by the Tom1-Tollip complex. Biochem. Biophys. Res. Commun. 341: 143-149, 2006.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TOM1L1

Antigène: TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))

Autre désignation: TOM1L1

Sujet:

Synonyms: C-C motif chemokine 16, Chemokine CC-4, HCC-4, Chemokine LEC, IL-10-inducible chemokine, LCC-1, Liver-expressed chemokine, Lymphocyte and monocyte chemoattractant, LMC, Monotactin-1, MTN-1, NCC-4, Small-inducible cytokine A16, CCL16, ILINCK, NCC4, SCYA16

Tissue Specificity: Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma- activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.

Background: TOM1-like protein 1 is a protein that in humans is encoded by the TOM1L1 gene. Enables clathrin binding activity and protein kinase binding activity. Involved in negative regulation of mitotic nuclear division, positive regulation of protein phosphorylation, and signal transduction. Located in cytosol and endosome.

Poids moléculaire: 55 kDa

ID gène: 10040

UniProt: O75674