PIAS1 anticorps (AA 96-300)
Aperçu rapide pour PIAS1 anticorps (AA 96-300) (ABIN7602694)
Antigène
Voir toutes PIAS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 96-300
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Fonction
- Anti-E3 SUMO-protein ligase PIAS1 PIAS1 Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-E3 SUMO-protein ligase PIAS1 PIAS1 Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human PIAS1 recombinant protein (Position: Q96-K300).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
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Autre désignation
- PIAS1
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Sujet
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Background: E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene. It is mapped to 15q23. This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.
Gene Full Name: protein inhibitor of activated STAT 1
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Poids moléculaire
- 72 kDa
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ID gène
- 8554
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UniProt
- O75925
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Pathways
- Signalistation JAK/STAT, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
Antigène
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