MAL anticorps (C-Term)

N° du produit ABIN7602807

Cet anticorps Lapin Polyclonal détecte spécifiquement MAL dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour MAL anticorps (C-Term) (ABIN7602807)

Antigène: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAL anticorps

Épitope: C-Term

Fonction: Anti-MAL Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-MAL Antibody Picoband® (ABIN7602807). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human MAL, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
1. Alonso, M., Barton, D. E., Francke, U. MAL, a membrane protein associated with human T-cell differentiation, is encoded on human chromosome 2, region cen-q13. (Abstract) Cytogenet. Cell Genet. 46: 570 only, 1987. 2. Alonso, M. A., Barton, D. E., Francke, U. Assignment of the T-cell differentiation gene MAL to human chromosome 2, region cen-q13. Immunogenetics 27: 91-95, 1988. 3. Alonso, M. A., Weissman, S. M. cDNA cloning and sequence of MAL, a hydrophobic protein associated with human T-cell differentiation. Proc. Nat. Acad. Sci. 84: 1997-2001, 1987.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur MAL

Antigène: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Autre désignation: MAL

Sujet:

Synonyms: Semaphorin-3E, SEMA3E, KIAA0331, SEMAH

Tissue Specificity: Detected in the sinusoidal epithelium in the red pulp of spleen. Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.

Background: Myelin and lymphocyte protein is a protein that in humans is encoded by the MAL gene. The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

Poids moléculaire: 17 kDa

ID gène: 4118

UniProt: P21145

Pathways: Asymmetric Protein Localization