CCR1 anticorps (C-Term)

N° du produit ABIN7602861

Cet anticorps Lapin Polyclonal détecte spécifiquement CCR1 dans WB. Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour CCR1 anticorps (C-Term) (ABIN7602861)

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CCR1 anticorps

Épitope: C-Term

Fonction: Anti-CCR1 Antibody Picoband®

Attributs du produit: Anti-CCR1 Antibody Picoband® (ABIN7602861). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse CCR1, which shares 73.7% amino acid (aa) sequence identity with human CCR1, respectively.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
1. Charo, I. F., Ransohoff, R. M. The many roles of chemokines and chemokine receptors in inflammation. New Eng. J. Med. 354: 610-621, 2006. 2. Daugherty, B. L., Springer, M. S. The beta-chemokine receptor genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) cluster within 285 kb on human chromosome 3p21. Genomics 41: 294-295, 1997. 3. Gao, J.-L., Kuhns, D. B., Tiffany, H. L., McDermott, D., Li, X., Francke, U., Murphy, P. M. Structure and functional expression of the human macrophage inflammatory protein 1-alpha/RANTES receptor. J. Exp. Med. 177: 1421-1427, 1993.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur CCR1

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Autre désignation: CCR1

Sujet: C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.

Poids moléculaire: 41 kDa

ID gène: 12768

UniProt: P51675