S100A14 anticorps (C-Term)

N° du produit ABIN7602920

Cet anticorps anti-S100A14 est un anticorps Lapin Polyclonal détectant S100A14 dans IHC. Adapté pour Humain.

Aperçu rapide pour S100A14 anticorps (C-Term) (ABIN7602920)

Antigène: S100A14 (S100 Calcium Binding Protein A14 (S100A14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S100A14 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-S100A14 anticorps

Épitope: C-Term

Fonction: Anti-S100A14 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-A14 Antibody Picoband® (ABIN7602920). Tested in IHC applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human S100A14, which shares 93.8% amino acid (aa) sequence identity with mouse S100A14.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
1. Adam, P. J., Boyd, R., Tyson, K. L., Fletcher, G. C., Stamps, A., Hudson, L., Poyser, H. R., Redpath, N., Griffiths, M., Steers, G., Harris, A. L., Patel, S., Berry, J., Loader, J. A., Townsend, R. R., Daviet, L., Legrain, P., Parekh, R., Terrett, J. A. Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer. J. Biol. Chem. 278: 6482-6489, 2003. 2. Chen, H., Yu, D., Luo, A., Tan, W., Zhang, C., Zhao, D., Yang, M., Liu, J., Lin, D., Liu, Z. Functional role of S100A14 genetic variants and their association with esophageal squamous cell carcinoma. Cancer Res. 69: 3451-3457, 2009. 3. Pietas, A., Schluns, K., Marenholz, I., Schafer, B. W., Heizmann, C. W., Petersen, I. Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family. Genomics 79: 513-522, 2002.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur S100A14

Antigène: S100A14 (S100 Calcium Binding Protein A14 (S100A14))

Autre désignation: S100A14

Sujet:

Synonyms: ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB

Tissue Specificity: Brain, neural-specific.

Background: S100 calcium binding protein A14 (S100A14) is a protein that in humans is encoded by the S100A14 gene. This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function.

Poids moléculaire: 18 kDa

ID gène: 57402

Pathways: Activation of Innate immune Response, S100 Proteins