Septin 5 anticorps (C-Term)

N° du produit ABIN7602924

Cet anticorps Lapin Polyclonal détecte spécifiquement Septin 5 dans WB et FACS. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour Septin 5 anticorps (C-Term) (ABIN7602924)

Antigène: Septin 5 (SEPT5)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 5 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-Septin 5 anticorps

Épitope: C-Term

Fonction: Anti-SEPT5/SEPTIN5 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SEPT5/SEPTIN5 Antibody Picoband® (ABIN7602924). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human SEPT5/SEPTIN5, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL/mL, Human
Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human, Rat
1. Blaser, S., Jersch, K., Hainmann, I., Wunderle, D., Zgaga-Griesz, A., Busse, A., Zieger, B. Human septin-septin interaction: CDCrel-1 partners with KIAA0202. FEBS Lett. 519: 169-172, 2002. 2. Caltagarone, J., Rhodes, J., Honer, W. G., Bowser, R. Localization of a novel septin protein, hCDCrel-1, in neurons of human brain. Neuroreport 9: 2907-2912, 1998. 3. Dent, J., Kato, K., Peng, X.-R., Martinez, C., Cattaneo, M., Poujol, C., Nurden, P., Nurden, A., Trimble, W. S., Ware, J. A prototypic platelet septin and its participation in secretion. Proc. Nat. Acad. Sci. 99: 3064-3069, 2002.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur Septin 5

Antigène: Septin 5 (SEPT5)

Autre désignation: SEPTIN5

Sujet:

Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7

Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Background: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Poids moléculaire: 42 kDa

ID gène: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis