Synaptophysin anticorps (N-Term)

N° du produit ABIN7603135

L’anticorps Souris Monoclonal anti-Synaptophysin a été validé pour WB. Il convient pour détecter Synaptophysin dans des échantillons de Rat et Souris.

Aperçu rapide pour Synaptophysin anticorps (N-Term) (ABIN7603135)

Antigène: Synaptophysin (SYP)

Reactivité: Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Synaptophysin est non-conjugé

Application: Western Blotting (WB)

Clone: 3G12

Détail du produit anti-Synaptophysin anticorps

Épitope: N-Term

Fonction: Anti-SYP/Synaptophysin Antibody Picoband® (monoclonal, 3G12)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SYP/Synaptophysin Antibody Picoband® (monoclonal, 3G12) (ABIN7603135). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Synaptophysin, identical to the related mouse and rat sequences.

Isotype: IgG2b

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse, Rat1. Calhoun ME, Jucker M, Martin LJ, Thinakaran G, Price DL, Mouton PR (December 1996). "Comparative evaluation of synaptophysin-based methods for quantification of synapses". J. Neurocytol.25 (12): 821-8.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Synaptophysin

Antigène: Synaptophysin (SYP)

Autre désignation: SYP

Sujet:

Synonyms: MRXSYP|Major synaptic vesicle protein p38

Tissue Specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.

Background: SYP (Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22). The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38 kDa. It is present inneuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).

Poids moléculaire: 38 kDa

ID gène: 6855

UniProt: P08247, Q62277, P07825

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity