UIMC1 anticorps (ubiquitinated)

N° du produit ABIN7603469

Cet anticorps anti-UIMC1 est un anticorps Lapin Monoclonal détectant UIMC1 dans WB, IHC, IF et ICC. Adapté pour Humain.

Aperçu rapide pour UIMC1 anticorps (ubiquitinated) (ABIN7603469)

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp UIMC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: ADCH-21

Détail du produit anti-UIMC1 anticorps

Épitope: ubiquitinated

Fonction: Anti-RAP80 Monoclonal Antibody

Attributs du produit: Anti-RAP80 Monoclonal Antibody (ABIN7603469). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human RAP80 Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs) .

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Détails sur UIMC1

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Autre désignation: UIMC1

Sujet:

Synonyms: Tumor necrosis factor receptor superfamily member 12A,Fibroblast growth factor-inducible immediate-early response protein 14,FGF-inducible 14,Tweak-receptor,TweakR,CD266,TNFRSF12A,FN14,

Tissue Specificity: Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.

Poids moléculaire: 70,90 kDa

Pathways: Réparation de l'ADN, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus