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DDX58 anticorps

L’anticorps Lapin Monoclonal anti-DDX58 a été validé pour WB et IP. Il convient pour détecter DDX58 dans des échantillons de Humain.
N° du produit ABIN7604629

Aperçu rapide pour DDX58 anticorps (ABIN7604629)

Antigène

Voir toutes DDX58 Anticorps
DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Reactivité

  • 86
  • 42
  • 17
  • 2
  • 1
Humain

Hôte

  • 79
  • 10
  • 1
  • 1
Lapin

Clonalité

  • 72
  • 19
Monoclonal

Conjugué

  • 43
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp DDX58 est non-conjugé

Application

  • 75
  • 23
  • 18
  • 17
  • 14
  • 14
  • 11
  • 8
  • 6
  • 5
  • 4
  • 3
  • 1
Western Blotting (WB), Immunoprecipitation (IP)

Clone

ACEA-4
  • Fonction

    Anti-DDX58 Monoclonal Antibody

    Attributs du produit

    Anti-DDX58 Monoclonal Antibody (ABIN7604629). Tested in WB, IP applications. This antibody reacts with Human.

    Purification

    Affinity-chromatography

    Immunogène

    A synthesized peptide derived from human DDX58 Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.

    Isotype

    IgG
  • Indications d'application

    WB 1:500-2000
    IP 1:50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Reconstitution

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    Concentration

    0.5 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • Antigène

    DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

    Autre désignation

    DDX58

    Sujet

    Synonyms: Histone H2AX,H2a/x,Histone H2A.X,H2AFX,H2AX,

    Tissue Specificity: Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells.

    Poids moléculaire

    100-110 kDa

    UniProt

    O95786

    Pathways

    Activation of Innate immune Response, Hepatitis C
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