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Menin anticorps

Cet anticorps anti-Menin est un anticorps Lapin Monoclonal détectant Menin dans WB, IHC, IP, IF et ICC. Adapté pour Humain.
N° du produit ABIN7605542

Aperçu rapide pour Menin anticorps (ABIN7605542)

Antigène

Voir toutes Menin (MEN1) Anticorps
Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

Reactivité

  • 80
  • 37
  • 30
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 72
  • 4
  • 2
  • 2
  • 1
Lapin

Clonalité

  • 76
  • 5
Monoclonal

Conjugué

  • 41
  • 6
  • 6
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Menin est non-conjugé

Application

  • 53
  • 38
  • 26
  • 13
  • 13
  • 13
  • 8
  • 7
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone

ACBA-13
  • Fonction

    Anti-Menin MEN1 Monoclonal Antibody

    Attributs du produit

    Anti-Menin MEN1 Monoclonal Antibody (ABIN7605542). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

    Purification

    Affinity-chromatography

    Immunogène

    A synthesized peptide derived from human Menin Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL) -containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes.

    Isotype

    IgG
  • Indications d'application

    WB 1:1000-1:5000
    IHC 1:50-1:200
    ICC/IF 1:50-1:200
    IP 1:50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Reconstitution

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    Concentration

    Lot specific

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • Antigène

    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

    Autre désignation

    MEN1

    Sujet

    Synonyms: Cytochrome b-245 heavy chain,1.-.-.-,CGD91-phox,Cytochrome b (558) subunit beta,Cytochrome b558 subunit beta,Heme-binding membrane glycoprotein gp91phox,NADPH oxidase 2,Neutrophil cytochrome b 91 kDa polypeptide,Superoxide-generating NADPH oxidase heavy chain subunit,gp91-1,gp91-phox,p22 phagocyte B-cytochrome,CYBB,NOX2,

    Tissue Specificity: Detected in neutrophils (at protein level). .

    Poids moléculaire

    47 kDa

    UniProt

    O00255

    Pathways

    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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