RAD50 anticorps
Aperçu rapide pour RAD50 anticorps (ABIN7606123)
Antigène
Voir toutes RAD50 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Rad50 Monoclonal Antibody
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Attributs du produit
- Anti-Rad50 Monoclonal Antibody (ABIN7606123). Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human Rad50 Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A.
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Isotype
- IgG
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Indications d'application
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WB 1:500-1:2000
ICC/IF 1:50-1:200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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Concentration
- Lot specific
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
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Autre désignation
- RAD50
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Sujet
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Synonyms: Ubiquitin-like modifier-activating enzyme ATG7,ATG12-activating enzyme E1 ATG7,Autophagy-related protein 7,APG7-like,hAGP7,Ubiquitin-activating enzyme E1-like protein,ATG7,APG7L,
Tissue Specificity: Widely expressed, especially in kidney, liver, lymph nodes and bone marrow. .
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Poids moléculaire
- 35 kDa
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UniProt
- Q92878
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Pathways
- Réparation de l'ADN, Protein targeting to Nucleus
Antigène
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