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CCR1 anticorps (Biotin)

Cet anticorps Human Chimeric détecte spécifiquement CCR1 dans WB et FACS. Il présente une réactivité envers Humain.
N° du produit ABIN7608073

Aperçu rapide pour CCR1 anticorps (Biotin) (ABIN7608073)

Antigène

Voir toutes CCR1 Anticorps
CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Reactivité

  • 59
  • 18
  • 3
Humain

Hôte

  • 47
  • 12
  • 6
  • 4
Human, Lapin

Clonalité

  • 50
  • 18
  • 1
Chimeric

Conjugué

  • 41
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CCR1 est conjugé à/à la Biotin

Application

  • 37
  • 32
  • 23
  • 20
  • 8
  • 7
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)

Clone

DMC465
  • Fonction

    Biotinylated Anti-CCR1 antibody(DMC465), IgG1 Chimeric mAb

    Purification

    Purified from cell culture supernatant by affinity chromatography

    Isotype

    IgG1
  • Indications d'application

    Flow Cyt 1:100, WB 1:1000

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Date de péremption

    12 months
  • Antigène

    CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

    Autre désignation

    CCR1

    Sujet

    This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]

    UniProt

    P32246
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