Cadherin 5 anticorps (AA 601-700) (Cy5)

N° du produit ABIN729347

L’anticorps Lapin Polyclonal anti-Cadherin 5 a été validé pour WB, FACS, IF (p) et IF (cc). Il convient pour détecter Cadherin 5 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Cadherin 5 anticorps (AA 601-700) (Cy5) (ABIN729347)

Antigène: Cadherin 5 (CDH5)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 5 est conjugé à/à la Cy5

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-Cadherin 5 anticorps (Cy5)

Épitope: AA 601-700

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse vascular endothelial cadherin

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Cadherin 5

Antigène: Cadherin 5 (CDH5)

Autre désignation: VE Cadherin

Sujet:

Synonyms: 7B4, Vec, VECD, Cd144, VEcad, VE-Cad, AA48225, Cadherin-5, Vascular endothelial cadherin, VE-cadherin, Cdh5

Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

ID gène: 12562

UniProt: P55284

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2