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ALDH1A1 anticorps (AA 315-434) (CF®740)

L’anticorps Souris Monoclonal anti-ALDH1A1 a été validé pour WB, IHC et IHC (fp). Il convient pour détecter ALDH1A1 dans des échantillons de Humain.
N° du produit ABIN7649327

Aperçu rapide pour ALDH1A1 anticorps (AA 315-434) (CF®740) (ABIN7649327)

Antigène

Voir toutes ALDH1A1 Anticorps
ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reactivité

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Humain

Hôte

  • 89
  • 43
  • 3
Souris

Clonalité

  • 80
  • 55
Monoclonal

Conjugué

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Cet anticorp ALDH1A1 est conjugé à/à la CF®740

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

ALDH1A1-1381
  • Épitope

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    AA 315-434

    Fonction

    ALDH1A1 (Aldehyde Dehydrogenase 1A1) (ALDH1A1/1381), CF740 conjugate

    Attributs du produit

    Aldehyde dehydrogenase 1 family member A1 (ALDH1A1), also known as retinal dehydrogenase 1, belongs to the aldehyde dehydrogenase enzyme family, which is involved in the metabolism of alcohol. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Purified recombinant fragment of human ALDH1A1 (aa 315-434)

    Isotype

    IgG1
  • Indications d'application

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Immunohistology (formalin): 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

    Commentaires

    Positive Control: HepG2 or A549 cells. Colon or Testicular Carcinoma.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % rBSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

    Autre désignation

    Aldehyde dehydrogenase 1

    Sujet

    Synonyms: Aldehyde dehydrogenase family 1 member A1, ALDH1A1, Retinal dehydrogenase 1, Retinaldehyde Dehydrogenase 1, Epididymis Luminal Protein

    Gene Symbol: ALDH1A1

    Poids moléculaire

    56 kDa

    ID gène

    216

    UniProt

    P00352

    Pathways

    Dopaminergic Neurogenesis
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