AKR1B1 anticorps (CF®568)

N° du produit ABIN7649340

Cet anticorps anti-AKR1B1 Monoclonal Souris conjugué à CF®568 (Clone CPTC-AKR1B1-3) (ABIN7649340) détecte spécifiquement AKR1B1 dans WB, IHC, IF et IHC (fp). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour AKR1B1 anticorps (CF®568) (ABIN7649340)

Antigène: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AKR1B1 est conjugé à/à la CF®568

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: CPTC-AKR1B1-3

Détail du produit anti-AKR1B1 anticorps (CF®568)

Fonction: Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker)(CPTC-AKR1B1-3), CF568 conjugate

Attributs du produit: Aldo-keto Reductase Family 1 Member B1 (AKR1B1), also known as aldose reductase or aldehyde reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human full-length AKR1B1 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: 293T, HEK293, A431, HeLa, HepG2, MOLT4, Jurkat and Raji whole cell lysates, Human Kidney, Human colon carcinoma tissue.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur AKR1B1

Antigène: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Autre désignation: Aldo-keto Reductase Family 1 Member B1

Sujet:

Synonyms: Aldo-keto reductase family 1 member B1, AKR1B1, Aldehyde Reductase 1, Aldose reductase, Lii5-2 CTCL tumor antigen, low Km aldose reductase

Gene Symbol: AKR1B1

Poids moléculaire: 37 kDa

ID gène: 231

UniProt: P15121

Pathways: Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process