Annexin a1 anticorps (CF®488A)

N° du produit ABIN7649540

L’anticorps Souris Monoclonal anti-Annexin a1 a été validé pour IHC, FACS et IHC (fp). Il convient pour détecter Annexin a1 dans des échantillons de Humain.

Aperçu rapide pour Annexin a1 anticorps (CF®488A) (ABIN7649540)

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Annexin a1 est conjugé à/à la CF®488A

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: 6E4-3

Détail du produit anti-Annexin a1 anticorps (CF®488A)

Fonction: Annexin A1 / (Hairy Cell Leukemia Marker)(6E4/3), CF488A conjugate

Attributs du produit: Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Mixture of native proteins from human bone tissues

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: HeLa, A431, K562 cells, human esophagus, placenta and prostate tissues.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur Annexin a1

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Autre désignation: Annexin A1

Sujet:

Synonyms: Annexin-1, Calpactin-2, Chromobindin-9, Phospholipase A2 inhibitory protein, LPC1, p35

Gene Symbol: ANXA1

Poids moléculaire: 35 kDa

ID gène: 301

UniProt: P04083

Pathways: Hormone Transport