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CALB1 anticorps (AA 7-96) (CF®405S)

Cet anticorps Souris Monoclonal détecte spécifiquement CALB1 dans . Il présente une réactivité envers Humain.
N° du produit ABIN7650277

Aperçu rapide pour CALB1 anticorps (AA 7-96) (CF®405S) (ABIN7650277)

Antigène

Voir toutes CALB1 Anticorps
CALB1 (Calbindin (CALB1))

Reactivité

  • 84
  • 41
  • 37
  • 10
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 60
  • 40
  • 1
  • 1
Souris

Clonalité

  • 52
  • 48
  • 1
Monoclonal

Conjugué

  • 57
  • 9
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CALB1 est conjugé à/à la CF®405S

Application

Veuillez nous consulter SVP

Clone

CALB1-2364
  • Épitope

    • 22
    • 12
    • 8
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 7-96

    Fonction

    Calbindin 1 (CALB1)(CALB1/2364), CF405S conjugate

    Attributs du produit

    Calbindin 1, also known as calbindin D28K, is a member of a family of calcium binding proteins. This protein family also includes calmodulin, calbindin 2, S-100, and troponin C. Calbindin 1 is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, calbindin 1 acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, calbindin 1 modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, calbindin 1 has been implicated to play a role in apoptosis and microtubule function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant fragment (around aa 7-96) of human CALB1 protein

    Isotype

    IgG1, kappa
  • Indications d'application

    For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

    Commentaires

    Positive Control: 293T or HepG2 cells. Prostate, Lung, Pancreas, Kidney and Liver.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    CALB1 (Calbindin (CALB1))

    Autre désignation

    Calbindin 1

    Sujet

    Synonyms: Calbindin, Calbindin 1, Calbindin D28, Calbindin D28K, CALB1, Vitamin D dependent calcium binding protein

    Gene Symbol: CALB1

    Poids moléculaire

    52 kDa

    ID gène

    793

    UniProt

    P05937
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