CALB1 anticorps (AA 7-96) (Biotin)
Aperçu rapide pour CALB1 anticorps (AA 7-96) (Biotin) (ABIN7650298)
Antigène
Voir toutes CALB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 7-96
-
Fonction
- Calbindin 1 (CALB1)(CALB1/2364), Biotin conjugate
-
Attributs du produit
- Calbindin 1, also known as calbindin D28K, is a member of a family of calcium binding proteins. This protein family also includes calmodulin, calbindin 2, S-100, and troponin C. Calbindin 1 is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, calbindin 1 acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, calbindin 1 modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, calbindin 1 has been implicated to play a role in apoptosis and microtubule function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
Immunogène
- Recombinant fragment (around aa 7-96) of human CALB1 protein
-
Isotype
- IgG1, kappa
-
-
-
-
Indications d'application
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
-
Commentaires
-
Positive Control: 293T or HepG2 cells. Prostate, Lung, Pancreas, Kidney and Liver.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.1 mg/mL
-
Buffer
- PBS, 0.1 % BSA, 0.05 % azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
Stockage commentaire
-
Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
Date de péremption
- 24 months
-
-
- CALB1 (Calbindin (CALB1))
-
Autre désignation
- Calbindin 1
-
Sujet
-
Synonyms: Calbindin, Calbindin 1, Calbindin D28, Calbindin D28K, CALB1, Vitamin D dependent calcium binding protein
Gene Symbol: CALB1
-
Poids moléculaire
- 52 kDa
-
ID gène
- 793
-
UniProt
- P05937
Antigène
-