Calnexin anticorps (N-Term) (CF®647)
Aperçu rapide pour Calnexin anticorps (N-Term) (CF®647) (ABIN7650423)
Antigène
Voir toutes Calnexin (CANX) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-300, N-Term
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Fonction
- Calnexin (Endoplasmic Reticulum Marker) (CANX/1543), CF647 conjugate
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Attributs du produit
- Calnexin is a type-I integral membrane protein of the endoplasmic reticulum (ER). It is a calcium-binding chaperone protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300)
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Positive Control: HeLa, MCF-7 or U2OS cells. Kidney or small intestine.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- Calnexin (CANX)
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Autre désignation
- Calnexin
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Sujet
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Synonyms: Calnexin, CANX, IP90, Major histocompatibility complex class I antigen-binding protein p88
Gene Symbol: CANX
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Poids moléculaire
- 67 kDa (predicted), 80-90 kDa (observed)
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ID gène
- 821
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UniProt
- P27824
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Pathways
- Signalisation MAPK, Thyroid Hormone Synthesis
Antigène
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