CTNNA1 anticorps (CF®740)

N° du produit ABIN7650594

Cet anticorps anti-CTNNA1 Monoclonal Souris conjugué à CF®740 (Clone 1G5) (ABIN7650594) détecte spécifiquement CTNNA1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CTNNA1 anticorps (CF®740) (ABIN7650594)

Antigène: CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTNNA1 est conjugé à/à la CF®740

Application: Western Blotting (WB)

Clone: 1G5

Détail du produit anti-CTNNA1 anticorps (CF®740)

Fonction: Catenin, alpha-1 (CTNNA1) (1G5), CF740 conjugate

Attributs du produit: Alpha-E-catenin (also known as Alpha-1 catenin) is part of the catenin family, a large family of Ca2 -dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-E-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-E-catenin forms a heterodimer with beta-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-E-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Human alpha catenin fusion protein

Isotype: IgG1

Information d'application

Indications d'application: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

Commentaires:

Positive Control: HeLa, A431 or MCF-7 Cells.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur CTNNA1

Antigène: CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

Autre désignation: Alpha-1 catenin

Sujet:

Synonyms: Alpha-E-catenin, Alpha-1 catenin, Cadherin-associated protein, Catenin alpha-1, CTNNA1

Gene Symbol: CTNNA1

Tissue Expression: Epithelial cells

Poids moléculaire: 102 kDa

ID gène: 1495

UniProt: P35221

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location