CD72 anticorps (CF®740)

N° du produit ABIN7651958

L’anticorps Souris Monoclonal anti-CD72 a été validé pour IHC et IHC (fp). Il convient pour détecter CD72 dans des échantillons de Humain.

Aperçu rapide pour CD72 anticorps (CF®740) (ABIN7651958)

Antigène: CD72 (CD72 Molecule (CD72))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD72 est conjugé à/à la CF®740

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: BU40

Détail du produit anti-CD72 anticorps (CF®740)

Fonction: CD72 (B Cell Marker)(BU40), CF740 conjugate

Attributs du produit: The C-type lectin superfamily member CD72 is a cell surface negative regulator of B cell activation from the pro-B through the mature B cell stage. CD72 serves as a receptor for CD5. The human CD72 gene encodes a transmembrane glycoprotein that contains an immunoreceptor tyrosine-based inhibition motif (ITIM). Upon tyrosine phosphorylation, the CD72 ITIM recruits SH2-containing phosphatases such as SHP-1, resulting in downregulation of cell activation. CD72-/- mice contain hyperproliferative B cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: HF B1 plasmacytoid cell line.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: K562 cel lysate. Tonsil or Lymph Node.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur CD72

Antigène: CD72 (CD72 Molecule (CD72))

Autre désignation: CD72

Sujet:

Synonyms: B cell differentiation antigen CD72, CD72b, CD72c, Ly-19, Ly-32, Ly-m19, LYB2, Lymphocyte antigen 32

Gene Symbol: CD72

Tissue Expression: B-cells

Poids moléculaire: 45 kDa

ID gène: 971

UniProt: P21854

Pathways: BCR Signaling