Decorin anticorps (AA 212-336)

N° du produit ABIN7653068

L’anticorps Souris Monoclonal anti-Decorin a été validé pour IHC et IHC (fp). Il convient pour détecter Decorin dans des échantillons de Humain.

Aperçu rapide pour Decorin anticorps (AA 212-336) (ABIN7653068)

Antigène: Decorin (DCN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Decorin est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: DCN-3523

Détail du produit anti-Decorin anticorps

Épitope: AA 212-336

Fonction: Decorin(DCN/3523)

Attributs du produit: Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF and is a direct or indirect negative modulator of TGF synthesis. Inhibition of Decorin core protein gene expression by the combination of IFN- and TNF may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. The human Decorin gene maps to chromosome 12q21. 33 and encodes a 359 amino acid protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human Decorin protein fragment (aa212-336)

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Human prostate or skin tissue (IHC).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur Decorin

Antigène: Decorin (DCN)

Autre désignation: Decorin

Sujet:

Synonyms: Bone proteoglycan II, CSCD, Dermatan sulphate proteoglycans II (DSPG2), PG40, PGII, PGS2, Proteoglycan core protein, SLRR1B, Small leucine rich protein 1B

Gene Symbol: DCN

Poids moléculaire: 43 kDa

ID gène: 1634

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process