Recombinant Desmin anticorps (CF®568)

N° du produit ABIN7653078

Cet anticorps anti-Desmin est un anticorps Lapin Monoclonal détectant Desmin dans IHC et IHC (fp). Adapté pour Humain, Rat, Poulet et Hamster.

Aperçu rapide pour Recombinant Desmin anticorps (CF®568) (ABIN7653078)

Antigène: Desmin (DES)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat, Poulet, Hamster

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmin est conjugé à/à la CF®568

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: DES-2960R

Détail du produit anti-Desmin anticorps (CF®568)

Fonction: Desmin (Muscle Cell Marker) (DES/2960R), CF568 conjugate

Attributs du produit: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alphalpha-helicalcoiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. The antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant full-length human DES protein

Isotype: IgG

Information d'application

Indications d'application: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA pH 9.0 for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

Commentaires:

Positive Control: SJRH30 Cells. Uterus or Leiomyosarcoma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: Desmin

Sujet:

Synonyms: CMD1I, CSM1, CSM2, DES, Intermediate filament protein

Gene Symbol: DES

Tissue Expression: Muscle

Poids moléculaire: 52 kDa

ID gène: 1674

UniProt: P17661