DPP4 anticorps (CF®740)

N° du produit ABIN7653186

Cet anticorps anti-DPP4 est un anticorps Souris Monoclonal détectant DPP4 dans FACS, IF et Func. Adapté pour Humain et Rat.

Aperçu rapide pour DPP4 anticorps (CF®740) (ABIN7653186)

Antigène: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DPP4 est conjugé à/à la CF®740

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone: 202-36

Détail du produit anti-DPP4 anticorps (CF®740)

Fonction: CD26(202-36), CF740 conjugate

Attributs du produit: Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Human T cell clone

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Immunohistology Frozen Only 0.5-1.0 μg/mL. Immunofluorescence 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Does not react with pig or sheep, others not tested. Optimal dilution for a specific application should be determined by user

Commentaires:

Positive Control: YT, HEP-G2 cells, and lymphocytes. Lymph nodes and tonsils.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur DPP4

Antigène: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Autre désignation: CD26

Sujet:

Synonyms: ADA-binding protein (ADABP), Adenosine deaminase complexing protein 2 (ADCP-2), Dipeptidyl peptidase 4, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase IV soluble form, Dipeptidyl peptidase, intestinal, Dipeptidylpeptidase 4, Dipeptidylpeptidase IV, DPP4, DPPIV, Intestinal dipeptidyl peptidase, T-cell activation antigen CD26, TP103

Gene Symbol: DPP4

Tissue Expression: Epithelial cells

Poids moléculaire: ~110 kDa

ID gène: 1803

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity