DBN1 anticorps (AA 150-281) (CF®488A)

N° du produit ABIN7653287

L’anticorps Souris Monoclonal anti-DBN1 a été validé pour WB, IHC et IHC (fp). Il convient pour détecter DBN1 dans des échantillons de Humain.

Aperçu rapide pour DBN1 anticorps (AA 150-281) (CF®488A) (ABIN7653287)

Antigène: DBN1 (Drebrin 1 (DBN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DBN1 est conjugé à/à la CF®488A

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: DBN1-2879

Détail du produit anti-DBN1 anticorps (CF®488A)

Épitope: AA 150-281

Fonction: Drebrin 1 (DBN1)(DBN1/2879), CF488A conjugate

Attributs du produit: Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer's disease and Down syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant fragment (aa 150-281) of human DBN1 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur DBN1

Antigène: DBN1 (Drebrin 1 (DBN1))

Autre désignation: Drebrin 1

Sujet:

Synonyms: Developmentally regulated brain protein, Drebrin 1, Drebrin, Drebrin E, Drebrin E2, Drebrin1, DrebrinE

Gene Symbol: DBN1

Tissue Expression: Heart|Skeletal Muscle|Brain|Kidney|Neurons|Pancreas|Placenta

Poids moléculaire: 120 kDa

ID gène: 1627

UniProt: Q16643

Pathways: Maintenance of Protein Location