GNAQ anticorps (CF®640R)

N° du produit ABIN7654735

Cet anticorps Souris Monoclonal détecte spécifiquement GNAQ dans . Il présente une réactivité envers Humain.

Aperçu rapide pour GNAQ anticorps (CF®640R) (ABIN7654735)

Antigène: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GNAQ est conjugé à/à la CF®640R

Application: Veuillez nous consulter SVP

Clone: GNAQ-2434

Détail du produit anti-GNAQ anticorps (CF®640R)

Fonction: Guanine nucleotide-binding protein alpha-q / GNAQ / G-ALPHA-q(GNAQ/2434), CF640R conjugate

Attributs du produit: GNAQis 359 amino acids long and is identical in all but 1 amino acid residue to the mouse protein. Analysis of human genomic DNA revealed an intronless sequence with strong homology to human GNAQ cDNA. In comparison to GNAQ cDNA, this genomic DNA sequence included several small deletions and insertions that altered the reading frame, multiple single based changes, and a premature termination codon in the open reading frame, all hallmarks of a processed pseudogene. Probes derived from human GNAQ cDNA sequence mapped both chromosomes 2 and 9 in higher constringency genomic blot analyses of DNA from a panel of human/rodent hybrid cell lines. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant full-length human GNAQ protein

Isotype: IgG2b, kappa

Information d'application

Indications d'application: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Commentaires:

Positive Control: HL-60, MOLT-4 and MCF-7 cells. Predominantly expressed in ovary, prostate, testis and colon.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur GNAQ

Antigène: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Autre désignation: G-Alpha-q

Sujet:

Synonyms: CMC1, G alpha Q, G protein alpha Q, GAQ, guanine nucleotide binding protein (G protein), q polypeptide, Guanine nucleotide-binding protein G(q) subunit alpha, SWS

Gene Symbol: GNAQ

Poids moléculaire: 45 kDa

ID gène: 2776

UniProt: P50148

Pathways: Signalistation JAK/STAT, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction