Integrin beta 4 anticorps (CF®740)
Aperçu rapide pour Integrin beta 4 anticorps (CF®740) (ABIN7655479)
Antigène
Voir toutes Integrin beta 4 (ITGB4) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- CD104(UM-A9), CF740 conjugate
-
Attributs du produit
- CD104 is beta 4 integrin. It is primarily expressed in epithelial cells. Together with alpha 6 integrin, it is the cell surface receptor for laminin, where it mediates cell adhesion. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
Immunogène
- Human squamous cell carcinoma (UM-SCC1)
-
Isotype
- IgG2a, kappa
-
-
-
-
Indications d'application
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Biological blockade partially blocks laminin binding. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user
-
Commentaires
-
Positive Control: A431 cells, squamous cell carcinoma, colon or placenta
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.1 mg/mL
-
Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Protect from light
-
Stock
- 4 °C
-
Stockage commentaire
-
Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
Date de péremption
- 24 months
-
-
- Integrin beta 4 (ITGB4)
-
Autre désignation
- CD104
-
Sujet
-
Synonyms: CD104, Integrin beta 4, ITGB4, GP150
Gene Symbol: ITGB4
Tissue Expression: Epithelial cells
-
Poids moléculaire
- 205 kDa
-
ID gène
- 3691
-
UniProt
- P16144
-
Pathways
- Integrin Complex
Antigène
-