IFNA2 anticorps (CF®647)

N° du produit ABIN7655631

Cet anticorps anti-IFNA2 est un anticorps Souris Monoclonal détectant IFNA2 dans . Adapté pour Humain.

Aperçu rapide pour IFNA2 anticorps (CF®647) (ABIN7655631)

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA2 est conjugé à/à la CF®647

Application: Veuillez nous consulter SVP

Clone: N39

Détail du produit anti-IFNA2 anticorps (CF®647)

Fonction: Interferon alpha-2 (IFNA2)(N39), CF647 conjugate

Attributs du produit: This antibody recognizes a protein of 16-27 kDa, identified as human interferon-alpha-2 (IFN-a2). Its epitope maps between aa112-148 of IFN-a2 (total aa172). This MAb is specific for IFN-a2 and does not cross-react with interferon-alpha-1. The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-a2. Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-a2 after viral infections. The IFN-a family consists of 24 or more genes or pseudo-genes. IFN-a2 is one of the two distinct families (I and II) of human IFN-a. The alpha-interferons are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.

Immunogène: Purified recombinant human IFN-alpha2

Isotype: IgG1, kappa

Information d'application

Indications d'application: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Commentaires:

Positive Control: Stimulated human peripheral blood mononuclear cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur IFNA2

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Autre désignation: Interferon Alpha-2

Sujet:

Synonyms: Alpha 2a interferon, IFN alpha, IFN-alpha-2, IFNA, IFNA2, IFNA2B, Interferon alpha 2a, Interferon alpha 2b, Interferon alpha-2, Interferon alpha-A, LeIF2, LeIFA

Gene Symbol: IFNA2

Tissue Expression: Lymphocytes|Monocytes/macrophages

Poids moléculaire: 16-27 kDa

ID gène: 3440

UniProt: P01563

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C