IL7R anticorps (AA 21-236)
Aperçu rapide pour IL7R anticorps (AA 21-236) (ABIN7655742)
Antigène
Voir toutes IL7R AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 21-236
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Fonction
- CD127 / IL7R (Marker of T-Reg Cells)(IL7R/2751)
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Attributs du produit
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Recombinant fragment (around aa 21-236) of human CD127 protein (IL7R)
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Isotype
- IgG2c, kappa
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Indications d'application
- ELISA: For coating, order Ab without BSA, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
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Commentaires
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Positive Control: K562, HeLa, Daudi or Jurkat cells. Tonsil, Lymph Node or Spleen.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, no BSA, no azide
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Agent conservateur
- Without preservative
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Stock
- -20 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- IL7R (Interleukin 7 Receptor (IL7R))
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Autre désignation
- CD127
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Sujet
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Synonyms: CD127, IL-7 receptor subunit alpha, IL-7R-alpha, IL7R, IL7RA, IL7R alpha, ILRA, Interleukin 7 receptor alpha chain, Interleukin 7 receptor
Gene Symbol: IL7R
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Poids moléculaire
- 52-72 kDa
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ID gène
- 3575
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UniProt
- P16871
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Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
Antigène
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