Moesin anticorps (CF®405S)
Aperçu rapide pour Moesin anticorps (CF®405S) (ABIN7657216)
Antigène
Voir toutes Moesin (MSN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Moesin(MSN/491), CF405S conjugate
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Attributs du produit
- Recognizes 78 kDa moesin protein. Moesin, a member of the talin-4. 1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Recombinant full-length human Moesin protein
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Positive Control: K562, HT-29, CH3LC or HUVEC cells. Uterus, Placenta, Tonsil, Melanoma, Testicular Carcinoma.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- Moesin (MSN)
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Autre désignation
- Moesin
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Sujet
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Synonyms: Membrane-organizing extension spike protein, Moesin/anaplastic lymphoma kinase fusion protein, MSLK fusion
Gene Symbol: MSN
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Poids moléculaire
- 78 kDa
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ID gène
- 4478
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UniProt
- P26038
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Pathways
- Asymmetric Protein Localization
Antigène
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