NKX2-8 anticorps (AA 10-123)

N° du produit ABIN7657992

Cet anticorps anti-NKX2-8 est un anticorps Souris Monoclonal détectant NKX2-8 dans WB. Adapté pour Humain.

Aperçu rapide pour NKX2-8 anticorps (AA 10-123) (ABIN7657992)

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NKX2-8 est non-conjugé

Application: Western Blotting (WB)

Clone: NKX28-2547

Détail du produit anti-NKX2-8 anticorps

Épitope: AA 10-123

Fonction: NKX2.8(NKX28/2547)

Attributs du produit: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Human recombinant NKX2.8 protein fragment (around aa 10-123)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Western blot 0.5 μg-1 μg/mL, Optimal dilution for a specific application should be determined.

Commentaires:

Positive Control: Human Liver, Kidney or Thyroid tissue (IHC).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur NKX2-8

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Autre désignation: NKX2.8

Sujet:

Synonyms: Homeobox protein NK 2 homolog H, Homeobox protein NK-2 homolog H, Homeobox protein Nkx 2.8, Homeobox protein Nkx-2.8, NK 2 homolog 8, NK 2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX28_HUMAN, NKX2G, NKX2H, OTTHUMP00000027959

Gene Symbol: NKX2-8

Poids moléculaire: 26 kDa

ID gène: 26257

UniProt: O15522